9/1/2023 0 Comments Companies like decode geneticsStefansson and Harper both say that their intent is to leave DeCode as it is, and to continue to allow it to publish its discoveries in scientific journals while giving Amgen access to the people doing the research to help speed its drug discovery efforts. company would now control Icelandic genetic samples. On Twitter, Albert Vernon Smith, a geneticist at the University of Iceland, wrote that there was unhappiness that a U.S. We have been struggling to discover drugs and diagnostics.” He said that he felt “privileged” that he will continue to run DeCode as a direct subsidiary of Amgen and that he hoped the larger company’s scale would protect DeCode from the vagaries of the market. “We have been struggling in the applied aspect of this. ![]() “I am convinced we are the most productive genetics discovery operation in the world,” said Stefansson in a telephone interview this morning. ![]() Still, though, making use of those discoveries was hard. The second DeCode has become a research powerhouse using a population genetics platform, making major discoveries about the genetics of Alzheimer’s and autism. It has since re-emerged, with new funding as a new company with the same name. In 2009, facing rising debts and a stock price that had fallen from its $18 IPO price to just 23 cents, it declared bankruptcy. At one point it was testing its own drug against cardiovascular disease.īut, in a classic biotechnology story, DeCode had trouble turning its science into a business. In 2000, it sported a market capitalization of $1.2 billion. Decode flew out of the box with a $200 million drug-finding collaboration with Roche. Founder, Kari Stefansson, a Harvard geneticist with the bearing of a Viking, sealed up a deal to use Iceland’s genealogical records to discover new genes. “That kind of information coming directly from humans is extremely compelling for people like me to have to make decisions,” says Harper.ĭeCode was a hot company from the moment it was founded in 1996. In a Nature paper, DeCode showed that mutations in a popular Alzheimer’s drug target called BACE could protect against the disease, and also against the normal loss of acuity that comes with aging. Harper says that DeCode’s work in Alzheimer’s is an example of how he would like to use the company’s technology. Sclerostin, a project Amgen is working on with UCB Pharma, is a similar but more under-the-radar story. The idea is that genetics can start to prove a drug will work before there is even a drug. Mutations that turn up the volume on the gene result in high cholesterol and larger risk of heart attacks those that make it stop working lower cholesterol and lifetime cholesterol risk. Researchers at several drug companies, including Sanofi, Pfizer and Merck as well as Amgen, have pointed to PCSK9 as their new ideal of a drug target. ![]() “Having that information that those targets are relevant in human disease as opposed to not having it and relying on animal models is a huge thing for us given that we can only explore a small number of drug targets in any given time.” “It was really working on targets like PCSK9 or our sclerostin program which are the two biggest assets in our pipeline that really drove home the immense value of having targets that have either been discovered or validated by the kind of human genetic analysis that Decode is a world expert in,” Harper says.
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9/1/2023 0 Comments Final cut pro x 10.3 tutorial![]() Define the clip, event, and library containers. Upgrade earlier versions of events and projects Importing Media. They are clear, concise and easy to follow and understand." - Samuel K.īelow are the videos in the course. Download the user guides as PDFs: Final Cut Pro User Guide (PDF) Motion User Guide (PDF) Compressor User Guide (PDF) You can also get the user guides from Apple Books: Final Cut Pro User Guide Motion User Guide Compressor User Guide Learn about the latest updates to Final Cut Pro, Motion, and Compressor: What’s New in Final Cut Pro 10.6. Apple Final Cut Pro X 10.3 Getting Started. "I think I have communicated this to you before but your tutorials are excellent. The lessons were all easy to digest and it really beat the heck out of reading the manual." - Paul A. ![]() "I found nuggets in almost every lesson that filled in a gap (pun intended) or made the magnetic timeline make a lot more sense. I would highly recommend this to anyone starting to use Final Cut Pro X. I watched the entire series in one sitting! What I especially liked was that I could pause the lesson and experiment/practice on my own files as I followed along with your tutorials. Video noise is typically a result of digital gain and appears as unwanted grain or artifacts in the video image. Complex tasks, like video analysis for object tracking or automatic cropping, are lightning fast on the Apple Neural Engine. Select version: Table of Contents Reduce video noise in Final Cut Pro Video noise is a common problem in video clips shot in low-light conditions or with small-sensor devices such as smartphones or action cameras. "Although I have been using Final Cut Pro for about a year, this is one of the best Final Cut Pro tutorials I have encountered. Fully optimized for the M1 Max and M1 Ultra on Mac Studio, Final Cut Pro transforms your video post-production with unrivaled performance. Thanks so much for making the tutorials available."- Rob M. Final Cut Pro X 10.3 Tutorial: Split Screen Creation - Pixel Perfect Class Ben Halsall: Final Cut Pro & Adobe Tutorials 29.1K subscribers Subscribe 4. This in-depth editing tutorial by expert editor Michael Wohl, dives beneath the 'Magnetic' timeline's surface to show you FCP X's many incredibly powerful editing modes and tools. However, with new ideas come new challenges and tools. "Your tutorials are so comprehensive, informative and easy to follow that I can’t think of anything else I would need to know to start serious editing. Select version: Table of Contents Set storage locations in Final Cut Pro You can set storage locations for each of your libraries. Final Cut Pro X, with its easy-to-use, freeform timeline, is truly revolutionary. Some feedback I've received about this tutorial: I hope this Final Cut Pro X training is helpful. 8/31/2023 0 Comments Amazing jam session jimmy kimmelWatch the full performance of “Insane” on Jimmy Kimmel Live above.Įnigmatic Society is out now via Sounds Of Crenshaw/Empire. The Amazing Jam Session Guys Show Up On Jimmy Kimmel With Trey Songz. ![]() The oozing swagger of the song’s lyrics is heightened by the musicians’ homely stage set up on Jimmy Kimmel Live! Dinner Party and Clemons hold an effortlessly soulful jam session blending together areas of each musician’s areas of expertise, from jazz to jazz and every element in between. Joined by singer Ant Clemons, Dinner Party demonstrated their growth with an intimate performance of the single “Insane.” As Clemons sings, “Hella glad you made it / Shot a clock, I’m faded / Be my designated / Call your driver, baby / ‘Cause that body drives me crazy,” the listener is hocked in with the buttery smooth lines. The Jam Session is a music-themed party for all land animals and was first introduced on April 25, 2013. Flisadam Pointer Contributing Writer Facebook Instagram Twitter. Grab your guitar, ukulele or piano and jam along in no time. Dinner Party Holds A Soulful Jam Session On ‘Jimmy Kimmel’ With A Performance Of ‘Insane’ With Ant Clemons. Trey Songz, Juicy J & Aloe Blacc.: Fm, E, A, D. On their latest project, Enigmatic Society, they are looking to outdo themselves. Chords for The Amazing Jam Session Guys feat. ![]() ![]() A video had surfaced online of these three random guys in Texas during an impromptu jam session they taped while in front of a supermarket. Fresh off of their Coachella weekend one performance, supergroup Dinner Party headed over to Jimmy Kimmel Live! to deliver yet another powerful set, this time for the fans at home.Ĭomprised of saxophonist Kamasi Washington, multi-instrumentalist Terrace Martin, DJ/producer 9th Wonder, and keyboardist Robert Glasper, the musical powerhouse’s self-titled debut album showcased just how much further the industry veterans could push themselves. Trey Songz, Juicy J and Aloe Blacc all took part in a jam session on Jimmy Kimmel Live this past week. 8/31/2023 0 Comments Gulf breeze bait and tackle![]() He gave personal shoutouts to individuals, including state Sen. “We're thrilled to be joined tonight by many outstanding Republican leaders,” Trump said. Trump Shouts Out Sarasota GOP Leaders Jacob President Donald Trump returned to Sarasota and attracted some 23,000 people to the Sarasota Fairgrounds, showing a community that helped his rise to prominence in politics still holds a special place in his heart. “I do hope it helps bring more customers into stores and businesses but more importantly it gives families the chance to save some of their hard earned dollars on those items that are necessities for them and their children,” said Sen. Merchandise excused from sales tax includes the first $5 to $10 spent on bait, $15 on sunscreen or bug repellant, $25 on snorkels, goggles or swim masks, $30 on water bottles, lanterns, flashlights or tackle boxes, $40 on sporting equipment, $50 on bike helmets, hydration packs, sleeping bags, hammocks, camp stoves, camp chairs or safety flares, $75 on coolers, rods, reels, life jackets, paddles or oars, $100 on sunglasses, $200 on binoculars or tents, $250 on grills, $300 on surfboards or paddleboards, and $500 on canoes or kayaks. Exempt items include music and sporting events, movie tickets, state park entry, most live entertainment events and passes to fitness clubs. State economists figure nearly $54 million in sales tax relief will come over the course of the seven days. After the tough year we’ve all had, it’s a small token from the government to the people.” It’s a win-win to give Floridians a little savings and help local businesses. ![]() “I’m hoping the tax break encourages people to go for those summer activity purchases they may have been considering,” said state Rep. Lawmakers say the event should both be a welcome respite for many who spent much of the last year in quarantine and also give a boost to Florida retailers after what was a trying year for many businesses and an unpredictable one for all. Starting last Thursday, July 1, and continuing through Wednesday, July 7, the state has exempted certain purchases of outdoor items and event tickets from state sales tax. Freedom Week Brings Economic Boost Jacob Florida Legislature this year decided the days around Independence Day could best be celebrated with tax breaks. 8/31/2023 0 Comments Dhl tracking miamiDeutsche Post DHL is now one of the largest logistics companies in the world. The Deutsche Post logistics services were branded as DHL in 2003. A formal merger was completed in 2002, which protected the jobs of the 71,000 DHL Worldwide Express employees at the time. ![]() DHL became the first express delivery company to operate in China, after an agreement was reached with the Chinese government.ĭeutsche Post AG was founded in 1995, and by 1998 the huge German logistics company had acquired a minority stake in DHL. Up until 1979, DHL specialized in the deliver of documents, but its service expanded to parcel delivery with great success. Services were expanded to Europe in 1974, and by 1978, deliveries and pick-ups were being made in Africa, Latin America and Australia. New services were launched along the Pacific Rim, and among the main destinations serviced by DHL at this time were Hong Kong, Singapore and Japan. It was DHL that also pioneered express international air delivery services.ĭuring the 1970s, DHL underwent a rapid period of expansion. This service – which was initially provided by a single plane – allowed customs procedures to begin in advance of the arrival of shipments. Founded in San Francisco in 1969, DHL began relatively modestly by shipping cargo documents between San Francisco and Hawaii. ![]() About DHLĭHL takes its name from the first letter of the last names of each founder: Adrian Dalsey, Larry Hillblom and Robery Lynn. Among the other ways to track shipments are DHL Express SMS, DHL Speed Tracking and DHL eTrack. You can check on the status and location of consignments by using the DHL ActiveTracing tool – all you need is a DHL order code, reference number, consignment ID of licence plate. The online tool that DHL provides allows for the tracking of up to 10 shipments at once. All that is needed is a DHL tracking number, but it is also possible to track the status of pending deliveries by contacting DHL customer service. It is possible to track DHL Express shipments very easily on the Tracking USA website. And the entire service is completely free to use. It’s as simple as that! The Tracking USA website can be accessed anywhere in the world, and on almost any internet-connected devices. Enter the DHL tracking number and then click the ‘Track Now’ link, and you will be updated on the status and location of your shipment. ![]() Our user-friendly design makes things very simple. But it is now easy to track your DHL packages and shipments on the Tracking USA website. However, it can be hard to keep track of multiple shipments when they are being delivered by several different delivery companies. Buying goods is now a simple matter of clicking some links and providing credit card details. DHL Tracking – Copyrights by DHLThe continued growth of internet shopping has resulted in an expansion of global logistics networks and companies around the world. ![]() ![]() Perhaps the group’s love of travel is why they want a world without borders? Although can you really imagine a group of people getting angry enough about passports to tear their world apart? What a ludicrous notion.Īfter turning his nose up at the finest chicken livers in Slovakia, Morgenthau gets two text messages. They were first seen robbing a bank in Switzerland, and then having a lorrytop scrap on their way from Munich, and now the Flag Smashers are in Slovakia’s capital, Bratislava. The second conversation they have later in the episode is markedly different in tone, with our heroes saying they could never work with him, and Walker offering a slightly chilling warning – if they won’t join his team, they must keep out of his way. Walker wants to team up with Bucky and Sam, although as he reveals he tracked Redwing, technically US government property, just like him, it doesn’t seem like they’ve got a lot of choice. Photograph: Marvel Studios/Courtesy of Marvel Studios Enter Captain America and Battlestar who level things up – Bucky even gets his hands on the shield again, momentarily – before they all end up grounded and the baddies get away with whatever medicine and vaccines they have in those wagons. 2-4-6-8 motorwayīucky and Sam engage the eight Flag Smashers, led, as predicted, by Karli Morgenthau, but very quickly realise they’re outmatched. If you consider their first meeting, though – the Winter Soldier, on the roof of Sam’s car, grabbing the steering wheel out of his hand and trying to kill him – and this is practically a love-in. Sooner or later, they have to bond properly. I am a fan of the chemistry between Sebastian Stan and Anthony Mackie, although I hope the reliance on gags about Bucky being old, staring a lot and hating Redwing aren’t overplayed. There’s some expositional dialogue, a nice line about the big three – androids, aliens and wizards – and the definition of a sorcerer, and then they’re off to Munich, where the Flag Smashers have been sighted. The reunion between our eponymous heroes isn’t quite the grand affair we might have expected, consisting as it does of Bucky barging in to an aircraft hangar to harangue Sam about giving Cap’s shield away. Cheesy as it may be, it at least motivates Bucky in to action … Avengers, of sorts … Reassemble We meet Lamar Hoskins, who later reveals himself as Battlestar, new Cap’s Bucky, and an interview in which Walker offers a cringeworthy story about seeing Steve Rogers as a brother, despite having never met him. ![]() Instead of Battleship and drinking games, we get John Walker, Captain America, who is nervous ahead of a ceremony at his old high school in Georgia. John Walker (Wyatt Russell) and Olivia Walker (Gabrielle Byndloss). 8/31/2023 0 Comments Papyrus tree egypt![]() Plant careĪdd top soil or organic peat humus to the hole when you plant. In addition, if the "head" hits the ground it will likely root there and grow a new plant.īest in Zone 10, these plants also grow in Zone 9B, but can be damagedīy cold and look bad through winter. Papyrus takes almost any kind of light - from full sun to partial shade - but seems to do best with a few hours of shade in the hottest period of the day, midday to mid-afternoon.įind a sheltered spot out of the wind - the tall stems can bend and break and detract from the plant's good looks. ![]() Heights range from 2 to 10 feet depending on variety. TheyĬan be invasive, so avoid planting near wetlands or preserves. These plants were known inĪncient times as bulrushes and the stems were used to make paper.Ī somewhat shorter variety (pictured below) is often called "Umbrella Sedge" (Cyperus alternifolis).Īll are spreading plants so growing in a contained area is best. It's pictured above.Ī very impressive plant with stalks as much as 10 feet tall topped withįeathery fluffs of cascading greenery. This an excellent choice for areas that stay moist after a rain since the plant doesn't mind "wet feet." The most whimsical one of the bunch is the Egyptian or giant variety (Cyperus papyrus). Regular irrigation and soil amendments to help hold moisture will To have a water garden to grow it well - simply a sheltered spot with Though it's sometimes used as a marginal pond plant, you don't have This is a great plant for a casual, eclectic landscape, but it won't work well for people who like everything "just so" in a more formal setting. Like bougainvillea, the bracts are the showy, ornamental part of the plant. The plant blooms during warm months with tiny, inconspicuous flowers. It forms an attractive clump of stalks with a grassy top that's actually made up of flower bracts. 8/31/2023 0 Comments Simple turkey coloring pages![]() Today’s colouring pages for grown ups, were created for you again, by the seriously talented Easy Peasy and Fun! And look at what else she has for you – stunning Dream Catcher Colouring Pages. Coloring involves control of numerous body senses simultaneously, which is a challenge for little learning kids. I have been asked a number of times what pens we use and have (I am NOT being paid to promote these, we genuinely love our set) – we have this set from Faber Castell, they are brilliant and I highly recommend them! (affiliate links)Īlso LOVE the look of this Thankful For colouring book for Grown Ups! A great way to relax and reflect on the year and think about the things we are thankful for! All these free turkey coloring pages for kids will boost creativity and develop amazing hand-eye coordination, enhanced motor skills, and focus. ![]() We also have some great KIDS TURKEY CRAFTS for you to browse! Or these Leaf Crafts – many of which would be wonderful for Thanksgiving too!Ĭlick here to down load your Leaf Mandala and Thanksgiving Turkey (and without writing here) colouring pages We have LOTS more Colouring Pages for Grown Ups for you to explore! then also check out the links below for some wonderful Dream Catchers! A great one to keep the kids busy whilst any final thanks giving preparations are going on! So choose today from our lovely lovely lovely Leaf Mandala or the Turkey. Save the file to your computer in the folder that you want to. Click the download button in the toolbar at the bottom of the page. To print any of these coloring pages, use the prompts within your browser to get an ad-free page printed off. Whether you're looking for funny turkeys or even cooked turkeys you'll find it here. Click the link for each one of the pages you want to download. Turkeys, turkeys, and more turkeys You'll find a ton of turkey coloring pages here that feature all kinds of turkeys. Inside you’ll find lots of fun designs that picture Thanksgiving themed meals and scenes. How to Download These Thanksgiving Coloring Pages. Followed by two versions of a beautiful Thanks Giving Turkey. There are 15 festive Thanksgiving images to choose from, all bundled together into one easy to download PDF file. 51 Free Thanksgiving Turkey Coloring Pages Free turkey Thanksgiving coloring sheets that you can download and print. Loose yourself in Firey Autumn Colours or explore greens and yellows. Through coloring, we celebrate gratitude, strengthen family bonds, and create cherished. As you embark on this coloring adventure, let your creativity soar, infusing your turkey pages with your unique style and personal expression. I simply ADORE the Leaf Mandala that we have for you today. Turkey coloring pages offer a delightful and immersive experience, combining artistry, history, and mindfulness. Today it is all about LEAVES and THANKS GIVING. Yes yes yes, our obsession with colouring pages for Grown Ups continue. 8/31/2023 0 Comments Ary seasons![]() Using her wits and courage, Ary will have to overcome monstrous enemies, secret plots, and stuffy traditions to save Valdi and bring balance to the world once more. Ary and the Secret of Seasons is an award-winning adventure game following a young girl named Aryelle, or Ary, as she journeys across the great world of Valdi. They formed the original Guardians of Seasons, a secretive organization now steeped in history and legend.Īfter a mysterious force throws the seasons of Valdi into disarray, Ary decides to assist the Guardians of Seasons and sets out to find the source of the mayhem. To ensure the mage's imprisonment, four great sages swore to keep watch and protect the Vault. After a great struggle, he was defeated by the Legendary Warrior and sealed inside the Vault, imprisoned for all eternity. Ary and the Secret of Seasons is an award-winning adventure game following a young girl named Aryelle, or Ary, as she journeys across the great world of Valdi. Long ago, the world of Valdi was threatened by an evil mage. Ary will learn to control the seasons and use them to defeat enemies, overcome obstacles, and solve complex puzzles on her adventure across Valdi. By becoming the Guardian of Winter, Ary gains the ability to manipulate the seasons around her. Journey across the magnificent world of Valdi!Īry and the Secret of Seasons PS4 is an award-winning adventure game following a young girl named Aryelle, or Ary, as she journeys across the great world of Valdi. A beautiful visual style combined with an enchanting soundtrack creates a lingering atmosphere that will surely become a memorable gameplay experience. Ary and the Secret of Seasons All Bosses (PS4, Switch, XB1) WishingTikal 664K subscribers Subscribe 4. Ary’s skills will be put to the test as she encounters foes looking to thwart her progress – from local inhabitants to hulking behemoths, she will use all the tools at her disposal to overcome monumental obstacles. Leap between ecosystems to bend the world and seasons to her needs. Manipulate the world around Ary with her environmental powers. Using her wits and courage, Ary will have to overcome monstrous enemies, secret plots, and stuffy traditions to save Valdi and bring balance to the world once more. ![]() As she ventures through uncharted locations across Valdi, Ary will discover secrets and hidden meanings behind the Guardian of Seasons. After a mysterious force throws the seasons of Valdi into disarray, Ary decides to assist the Guardians of Seasons and sets out to find the source of the mayhem. Ary is recruited to help the Guardians of Seasons, an old organization caught up by rigid traditions. Ary and the Secret of Seasons - Official Gameplay Overview gamescom 2020 - YouTube Take control of seasons as Ary and the Secret of Seasons, an award-winning adventure game set in a. Harnessing the power of the seasons, Ary can traverse sweeping landscapes in search of new destinations, solving amazing environmental puzzles to progress. 8/31/2023 0 Comments Aura bora shark tank net worth![]() The Voges are appearing in the Tank at a perfect stage for their business. Which Shark will want to swim in sparkling waters? Will Sharks Drink Up and Invest? While their distributors may be trying to get that done for them, a Shark could accelerate the process for them. What the Voges need is to get into Krogers and Publix and other national chains. I will definitely pick some up as they’re available at one of my local markets. I find variety appealing and these flavors sound interesting enough to try. I drink quite a bit of sparkling water since going keto at the beginning of 2021. The Voges did very well getting started in 2020,now they want a Shark to get them more national distribution – perhaps even in Delaware! My Take on Aura Bora Sparkling Water You can also buy a 12 pack for $30 on Amazon. If you see it in a store, it will cost you about three bucks a can. That’s not bad for being in business less than a year.Īura Bora Sparkling Water comes in five flavors: Cactus Rose, Lavender Cucumber, Peppermint Watermelon, Basil Berry, and Lemongrass Coconut. The couple also got distribution in 49 states (not Delaware) through natural food distributors KeHE and UNFI. They got a high powered branding company to design their cans, with Madeline’s help. Starting a business during a global pandemic doesn’t sound like a good idea, but the Voges made the best of it. They decided – perhaps foolishly -to start selling their creations in January, 2020, right at the beginning of the Covid-19 Pandemic. The couple decided to start experimenting with some herbs they had in their pantry and concocted some funky flavors. They like sparkling water so much, they have their own Soda Stream. ![]() ![]() Paul and Maddie Voge created Aura Bora Sparkling Water while experimenting in their kitchen. |
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